Research

Theoretical Framework

THEORETICAL FRAMEWORK FOR THE CLINICAL APPLICATIONS OF MOLLII

The Mollii method is an innovative approach for non-invasive electrical stimulation to reduce spasticity and improve motor function in persons with a lesion in the central nervous system. The theoretical framework below describes the background of the Mollii concept.

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Studies with Mollii Suit

ELECTRICAL STIMULATION AS A TREATMENT FOR SPASTICITY IN CHILDREN (2014)
Sweden

The study was conducted as a qualitative study with gathering of data through a questionnaire of fifty-four children with cerebral palsy. The result of the study showed that the most pronounced effect of the treatment with the Mollii suit was reduced spasticity, as reported by 61% of patients. An improvement in overall mobility was reported by 48% and more than 30% experienced that they could easily trample the heels, lift their arms over their heads and/or straighten their hands and fingers.

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COST-EFFECTIVENESS ANALYSIS OF THE INERVENTIONS METHOD (2014)
Sweden
This study aimed to assess the cost-effectiveness of the Inerventions method (as per above study) and compare it with conventional medical treatments, such as baclofen, botolium toxin and surgery, for children with cerebral palsy in Sweden. Results indicate that the Inerventions method was more effective than all other treatments, and less costly than most other treatments.

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A CASE STUDY TO ASSESS THE EFFECTS OF AN ELECTRICAL STIMULATION SUIT ON THE FUNCTIONAL MOBILITY OF AN INDIVIDUAL WITH SECONDARY PROGRESSIVE MULTIPLE SCLEROSIS (2016)
London
This study showed that the patient had improved quality of movement in the upper extremity after a one hour of treatment with the Mollii suit. The study participant explained that “The Mollii suit lessens the battle between my left and right side, resulting in less energy needed for mobility”.

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NEUROMUSCULAR ELECTRICAL STIMULATION AND CONDUCTIVE EDUCATION (2016)
France
At the 9th World Congress of Conductive Education in Budapest, Mollii expert and Conductor Mira Auer presented her study from Pouilly-sur-Loire, France in 24 children. Mira has evaluated the combination of Conductive Education while using the Mollii suit.
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NATIONAL INSTITUTE FOR HEALTH AND CARE EXCELLENCE (NICE) REVIEW ON MOLLII SUIT FOR SPASTICITY (2017)
United Kingdom
Mollii was reviewed under NICE’s ‘MedTech Innovation Bulletin” in 2017. Their review can be found below.
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REPORT ON FOUR PATIENTS THAT USED MOLLII SUIT FOR SIX MONTHS (2015)
Västernorrland
Six adults with cerebral palsy were evaluated over a 6 month period in Sweden by physiotherapist Len Andersson. The report on four of them is attached as a PDF on this page.

NEUROFLEXOR
Stockholm
Spasticity can be very difficult to evaluate with the measuring protocols available and bias is difficult to avoid or eliminate. With this in mind, Mollii’s effect on hand spasticity was evaluated with a innovative measuring tool, NeuroFlexor. NeuroFlexor was developed and validated by scientists at the Karolinska Institute, Stockholm, as per research articles below.

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Learn More NeuroFlexor sensitivity (PDF 595KB)

NeuroFlexor was used on a patient with severe hand spasticity due to cerebral palsy. Scientists from the NeuroFlexor team were able to show a significant reduction of spasticity after a one hour session with the Mollii suit. Repeated tests with NeuroFlexor will be required to scientifically evaluate the Mollii Suit’s effect of hand spasticity. In the below PDF, results can be seen both before and after a one hour session with the Mollii suit, as measured by the NeuroFlexor.

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THE MOLLII-SUIT – A NOVEL METHOD USING RECIPROCAL INHIBITION ON CHILDREN WITH CEREBRAL PALSY, GFMCS IV-V. A 6 MONTH PROSPECTIVE STUDY
University hospital of Hvidovre, Copenhagen, Denmark
The purpose of this study was to investigate whether a novel method of using reciprocal inhibition affects range of motion and spasticity on children with cerebral palsy.

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LATEST RESEARCH ON MOLLII

An independent review of research on the neuro-physiological mechanisms the Mollii Suit uses and how it can be applied clinically for spasticity, dystonia as well as pain relief is out now. This review carried out by Dr Pennati, MD, PhD student and colleagues, within the Karolinska Institutet, Stockholm, Sweden was completed in October 2017 and funded by the Swedish Government innovation agency. The review provides an understanding of how Mollii’s sub-threshold, sensory electro-stimulation works based on current, relevant independent research.